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Multiple gene substitution by Target-AID base-editing technology in tomato

The use of Target activation-induced cytidine deaminase (Target-AID) base-editing technology with the CRISPR-Cas 9 system fused with activation-induced cytidine deaminase (AID) resulted in the substitution of a cytidine with a thymine. In previous experiments focusing on a single target gene, this s...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Hunziker, Johan, Nishida, Keiji, Kondo, Akihiko, Kishimoto, Sanae, Ariizumi, Tohru, Ezura, Hiroshi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686336/
https://ncbi.nlm.nih.gov/pubmed/33235312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77379-2
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