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Mechanosensing through direct binding of tensed F-actin by LIM domains

Mechanical signals transmitted through the cytoplasmic actin cytoskeleton must be relayed to the nucleus to control gene expression. LIM domains are protein-protein interaction modules found in cytoskeletal proteins and transcriptional regulators. Here we identify three LIM protein families (zyxin,...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Sun, Xiaoyu, Phua, Donovan Y. Z., Axiotakis, Lucas, Smith, Mark A., Blankman, Elizabeth, Gong, Rui, Cail, Robert C., de Los Reyes, Santiago Espinosa, Beckerle, Mary C., Waterman, Clare M., Alushin, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686152/
https://ncbi.nlm.nih.gov/pubmed/33058779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.09.022
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