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Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension

OBJECTIVES: To identify predictors of portal hypertension, liver transplantation, and death in North American youth with alpha-1-antitrypsin (AAT) deficiency, and compare with AAT deficiency patients elsewhere. STUDY DESIGN: The Childhood Liver Disease Research Network Longitudinal Observational Stu...

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מידע ביבליוגרפי
הוצא לאור ב:	J Pediatr
Main Authors:	Teckman, Jeffrey, Rosenthal, Philip, Hawthorne, Kieran, Spino, Cathie, Bass, Lee M., Murray, Karen F., Kerkar, Nanda, Magee, John C., Karpen, Saul, Heubi, James E., Molleston, Jean P., Squires, Robert H., Kamath, Binita M., Guthery, Stephen L., Loomes, Kathleen M., Sherker, Averell H., Sokol, Ronald J.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2020
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7686087/ https://ncbi.nlm.nih.gov/pubmed/32663593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2020.07.031
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Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension

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