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The Kappa Opioid Receptor Antagonist Aticaprant Reverses Behavioral Effects from Unpredictable Chronic Mild Stress in Male Mice

RATIONALE: Major depressive disorder is a leading cause of disability worldwide and is likely precipitated by chronic stress. Although many antidepressants are currently available, these drugs require weeks to months of daily administration before reduction of symptoms occur and many patients remain...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Jacobson, Moriah L., Wulf, Hildegard A., Browne, Caroline A., Lucki, Irwin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686052/
https://ncbi.nlm.nih.gov/pubmed/32894343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-020-05649-y
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