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Synergistic reduction in albuminuria in type 2 diabetic mice by esaxerenone (CS-3150), a novel nonsteroidal selective mineralocorticoid receptor blocker, combined with an angiotensin II receptor blocker

Esaxerenone is a novel selective mineralocorticoid receptor (MR) blocker that was recently approved in Japan to treat hypertension. In phase II and III studies, esaxerenone plus a renin–angiotensin system inhibitor markedly reduced the urinary albumin-to-creatinine ratio (UACR) in hypertensive patie...

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Detalhes bibliográficos
Publicado no:Hypertens Res
Main Authors: Arai, Kiyoshi, Morikawa, Yuka, Ubukata, Naoko, Sugimoto, Kotaro
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685977/
https://ncbi.nlm.nih.gov/pubmed/32616846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41440-020-0495-0
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