CYLD-mutant cylindroma-like basaloid carcinoma of the anus: a genetically and morphologically distinct class of HPV-related anal carcinoma

Rare reports of anal carcinoma (AC) describe histologic resemblance to cutaneous cylindroma, but mutations in the tumor suppressor CYLD, the gene responsible for familial and sporadic cylindromas, have not been systematically investigated in AC. Here, we investigate CYLD-mutant AC, focusing on molec...

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Udgivet i:Mod Pathol
Main Authors: Williams, Erik A., Montesion, Meagan, Sharaf, Radwa, Corines, James, Patel, Parth J., Gillespie, Brendan J., Pavlick, Dean C., Sokol, Ethan S., Alexander, Brian M., Williams, Kevin Jon, Elvin, Julia A., Ross, Jeffrey S., Ramkissoon, Shakti H., Hemmerich, Amanda C., Tse, Julie Y., Mochel, Mark C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685972/
https://ncbi.nlm.nih.gov/pubmed/32461623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-020-0584-2
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