CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features

Mutations in the tumor suppressor CYLD, known to be causative of cylindromas, were recently described in a subset of high-risk (hr) HPV-positive head and neck squamous cell carcinomas (HNSCC). Pathologic and genetic characterization of these CYLD-mutant carcinomas, however, remains limited. Here, we...

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Bibliografski detalji
Izdano u:Mod Pathol
Glavni autori: Williams, Erik A., Montesion, Meagan, Alexander, Brian M., Ramkissoon, Shakti H., Elvin, Julia A., Ross, Jeffrey S., Williams, Kevin Jon, Glomski, Krzysztof, Bledsoe, Jacob R., Tse, Julie Y., Mochel, Mark C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group US 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817524/
https://ncbi.nlm.nih.gov/pubmed/32892208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-020-00672-y
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