Metabolic Syndrome Alters the Cargo of Mitochondria-Related microRNAs in Swine Mesenchymal Stem Cell-Derived Extracellular Vesicles, Impairing Their Capacity to Repair the Stenotic Kidney

BACKGROUND: Coexisting metabolic syndrome (MetS) and renal artery stenosis (RAS) are linked to poor renal outcomes. Mesenchymal stem/stromal cell- (MSC-) derived extracellular vesicles (EVs) from lean animals show superior ability to repair the experimental MetS+RAS kidney compared to EVs from MetS...

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Détails bibliographiques
Publié dans:Stem Cells Int
Auteurs principaux: Farahani, Rahele A., Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L., Lerman, Amir, Lerman, Lilach O., Eirin, Alfonso
Format: Artigo
Langue:Inglês
Publié: Hindawi 2020
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685840/
https://ncbi.nlm.nih.gov/pubmed/33281903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8845635
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