Metabolic Syndrome Alters the Cargo of Mitochondria-Related microRNAs in Swine Mesenchymal Stem Cell-Derived Extracellular Vesicles, Impairing Their Capacity to Repair the Stenotic Kidney

BACKGROUND: Coexisting metabolic syndrome (MetS) and renal artery stenosis (RAS) are linked to poor renal outcomes. Mesenchymal stem/stromal cell- (MSC-) derived extracellular vesicles (EVs) from lean animals show superior ability to repair the experimental MetS+RAS kidney compared to EVs from MetS...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Farahani, Rahele A., Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L., Lerman, Amir, Lerman, Lilach O., Eirin, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685840/
https://ncbi.nlm.nih.gov/pubmed/33281903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8845635
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