The DEL-1/β3 integrin axis promotes regulatory T cell responses during inflammation resolution

FOXP3(+)CD4(+) regulatory T cells (Tregs) are critical for immune homeostasis and respond to local tissue cues, which control their stability and function. We explored here whether developmental endothelial locus-1 (DEL-1), which, like Tregs, increases during resolution of inflammation, promotes Tre...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Li, Xiaofei, Colamatteo, Alessandra, Kalafati, Lydia, Kajikawa, Tetsuhiro, Wang, Hui, Lim, Jong-Hyung, Bdeir, Khalil, Chung, Kyoung-Jin, Yu, Xiang, Fusco, Clorinda, Porcellini, Antonio, De Simone, Salvatore, Matarese, Giuseppe, Chavakis, Triantafyllos, De Rosa, Veronica, Hajishengallis, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685741/
https://ncbi.nlm.nih.gov/pubmed/32817592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137530
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