dmPFC-vlPAG projection neurons contribute to pain threshold maintenance and antianxiety behaviors

The dorsal medial prefrontal cortex (dmPFC) has been recognized as a key cortical area for nociceptive modulation. However, the underlying neural pathway and the function of specific cell types remain largely unclear. Here, we show that lesions in the dmPFC induced an algesic and anxious state. Usin...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Yin, Jun-Bin, Liang, Shao-Hua, Li, Fei, Zhao, Wen-Jun, Bai, Yang, Sun, Yi, Wu, Zhen-Yu, Ding, Tan, Sun, Yan, Liu, Hai-Xia, Lu, Ya-Cheng, Zhang, Ting, Huang, Jing, Chen, Tao, Li, Hui, Chen, Zhou-Feng, Cao, Jing, Ren, Rui, Peng, Ya-Nan, Yang, Juan, Zang, Wei-Dong, Li, Xiang, Dong, Yu-Lin, Li, Yun-Qing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685740/
https://ncbi.nlm.nih.gov/pubmed/32841213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127607
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