dmPFC-vlPAG projection neurons contribute to pain threshold maintenance and antianxiety behaviors

The dorsal medial prefrontal cortex (dmPFC) has been recognized as a key cortical area for nociceptive modulation. However, the underlying neural pathway and the function of specific cell types remain largely unclear. Here, we show that lesions in the dmPFC induced an algesic and anxious state. Usin...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Yin, Jun-Bin, Liang, Shao-Hua, Li, Fei, Zhao, Wen-Jun, Bai, Yang, Sun, Yi, Wu, Zhen-Yu, Ding, Tan, Sun, Yan, Liu, Hai-Xia, Lu, Ya-Cheng, Zhang, Ting, Huang, Jing, Chen, Tao, Li, Hui, Chen, Zhou-Feng, Cao, Jing, Ren, Rui, Peng, Ya-Nan, Yang, Juan, Zang, Wei-Dong, Li, Xiang, Dong, Yu-Lin, Li, Yun-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685740/
https://ncbi.nlm.nih.gov/pubmed/32841213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127607
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