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Age-related susceptibility to coronavirus infections: role of impaired and dysregulated host immunity

Human coronaviruses (hCoVs) cause severe respiratory illness in the elderly. Age-related impairments in innate immunity and suboptimal virus-specific T cell and antibody responses are believed to cause severe disease upon respiratory virus infections. This phenomenon has recently received increased...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Channappanavar, Rudragouda, Perlman, Stanley
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685716/
https://ncbi.nlm.nih.gov/pubmed/33085654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI144115
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