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Nanoparticle-complexed antimiRs for inhibiting tumor growth and metastasis in prostate carcinoma and melanoma

BACKGROUND: MiRNAs act as negative regulators of gene expression through target mRNA degradation or inhibition of its translation. In cancer, several miRNAs are upregulated and play crucial roles in tumorigenesis, making the inhibition of these oncomiRs an interesting therapeutic approach. This can...

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Bibliografiska uppgifter
I publikationen:J Nanobiotechnology
Huvudupphovsmän: Kunz, Manfred, Brandl, Madeleine, Bhattacharya, Animesh, Nobereit-Siegel, Lars, Ewe, Alexander, Weirauch, Ulrike, Hering, Doreen, Reinert, Anja, Kalwa, Hermann, Guzman, Juan, Weigelt, Katrin, Wach, Sven, Taubert, Helge, Aigner, Achim
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685669/
https://ncbi.nlm.nih.gov/pubmed/33228711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00728-w
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