Nanoparticle-complexed antimiRs for inhibiting tumor growth and metastasis in prostate carcinoma and melanoma

BACKGROUND: MiRNAs act as negative regulators of gene expression through target mRNA degradation or inhibition of its translation. In cancer, several miRNAs are upregulated and play crucial roles in tumorigenesis, making the inhibition of these oncomiRs an interesting therapeutic approach. This can...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Kunz, Manfred, Brandl, Madeleine, Bhattacharya, Animesh, Nobereit-Siegel, Lars, Ewe, Alexander, Weirauch, Ulrike, Hering, Doreen, Reinert, Anja, Kalwa, Hermann, Guzman, Juan, Weigelt, Katrin, Wach, Sven, Taubert, Helge, Aigner, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685669/
https://ncbi.nlm.nih.gov/pubmed/33228711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00728-w
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