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Transient Intestinal Colonization by a Live-Attenuated Oral Cholera Vaccine Induces Protective Immune Responses in Streptomycin-Treated Mice

Current mouse models for evaluating the efficacy of live oral cholera vaccines (OCVs) have important limitations. Conventionally raised adult mice are resistant to intestinal colonization by Vibrio cholerae, but germfree mice can be colonized and have been used to study OCV immunogenicity. However,...

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Bibliografski detalji
Izdano u:J Bacteriol
Glavni autori: Fakoya, Bolutife, Sit, Brandon, Waldor, Matthew K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685556/
https://ncbi.nlm.nih.gov/pubmed/32540930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00232-20
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