Oral immunization with a probiotic cholera vaccine induces broad protective immunity against Vibrio cholerae colonization and disease in mice

Oral cholera vaccines (OCVs) are being increasingly employed, but current killed formulations generally require multiple doses and lack efficacy in young children. We recently developed a new live-attenuated OCV candidate (HaitiV) derived from a Vibrio cholerae strain isolated during the 2010 Haiti...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: Sit, Brandon, Zhang, Ting, Fakoya, Bolutife, Akter, Aklima, Biswas, Rajib, Ryan, Edward T., Waldor, Matthew K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561597/
https://ncbi.nlm.nih.gov/pubmed/31150386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007417
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