A multi-component toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome

Host recognition of microbial components is essential in mediating an effective immune response. Cytosolic bacteria must secure entry into the host cytoplasm to facilitate replication, and in doing so, liberating microbial ligands which activate cytosolic innate immune sensors and the inflammasome....

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Mathur, Anukriti, Feng, Shouya, Hayward, Jenni A., Ngo, Chinh, Fox, Daniel, Atmosukarto, Ines I., Price, Jason D., Schauer, Kristina, Märtlbauer, Erwin, Robertson, Avril A.B., Burgio, Gaetan, Fox, Edward M., Leppla, Stephen H., Kaakoush, Nadeem O., Man, Si Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685251/
https://ncbi.nlm.nih.gov/pubmed/30531979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0318-0
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