Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

Severe cases of COVID-19 are characterized by a strong inflammatory process that may ultimately lead to organ failure and patient death. The NLRP3 inflammasome is a molecular platform that promotes inflammation via cleavage and activation of key inflammatory molecules including active caspase-1 (Cas...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Rodrigues, Tamara S., de Sá, Keyla S.G., Ishimoto, Adriene Y., Becerra, Amanda, Oliveira, Samuel, Almeida, Leticia, Gonçalves, Augusto V., Perucello, Debora B., Andrade, Warrison A., Castro, Ricardo, Veras, Flavio P., Toller-Kawahisa, Juliana E., Nascimento, Daniele C., de Lima, Mikhael H.F., Silva, Camila M.S., Caetite, Diego B., Martins, Ronaldo B., Castro, Italo A., Pontelli, Marjorie C., de Barros, Fabio C., do Amaral, Natália B., Giannini, Marcela C., Bonjorno, Letícia P., Lopes, Maria Isabel F., Santana, Rodrigo C., Vilar, Fernando C., Auxiliadora-Martins, Maria, Luppino-Assad, Rodrigo, de Almeida, Sergio C.L., de Oliveira, Fabiola R., Batah, Sabrina S., Siyuan, Li, Benatti, Maira N., Cunha, Thiago M., Alves-Filho, José C., Cunha, Fernando Q., Cunha, Larissa D., Frantz, Fabiani G., Kohlsdorf, Tiana, Fabro, Alexandre T., Arruda, Eurico, de Oliveira, Renê D.R., Louzada-Junior, Paulo, Zamboni, Dario S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2020
Soggetti:
Brief Definitive Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7684031/
https://ncbi.nlm.nih.gov/pubmed/33231615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201707
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi