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Ni-catalyzed asymmetric hydrogenation of N-aryl imino esters for the efficient synthesis of chiral α-aryl glycines

Chiral α-aryl glycines play a key role in the preparation of some bioactive products, however, their catalytic asymmetric synthesis is far from being satisfactory. Herein, we report an efficient nickel-catalyzed asymmetric hydrogenation of N-aryl imino esters, affording chiral α-aryl glycines in hig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Liu, Dan, Li, Bowen, Chen, Jianzhong, Gridnev, Ilya D., Yan, Deyue, Zhang, Wanbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683563/
https://ncbi.nlm.nih.gov/pubmed/33230219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19807-5
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