Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

OBJECTIVES: Long-chain fatty acids (LCFAs) released from adipocytes inhibit lipolysis through an unclear mechanism. We hypothesized that the LCFA receptor, FFAR4 (GPR120), which is highly expressed in adipocytes, may be involved in this feedback regulation. METHODS AND RESULTS: Liquid chromatography...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Metab
Autores principales: Husted, Anna Sofie, Ekberg, Jeppe H., Tripp, Emma, Nissen, Tinne A.D., Meijnikman, Stijn, O'Brien, Shannon L., Ulven, Trond, Acherman, Yair, Bruin, Sjoerd C., Nieuwdorp, Max, Gerhart-Hines, Zach, Calebiro, Davide, Dragsted, Lars O., Schwartz, Thue W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
Materias:
Brief Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683346/
https://ncbi.nlm.nih.gov/pubmed/33091626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101103
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares