Allelic Distribution of Genes for Apolipoprotein E and MTHFR in Patients with Alzheimer’s Disease and Their Epistatic Interaction

BACKGROUND: Genetic risk factors play an important role in the pathogenesis of Alzheimer’s disease (AD). However, the gene-gene interaction (epistasis) between specific allelic variants is only partially understood. OBJECTIVE: In our study, we examined the presence of the ɛ4 allele of apolipoprotein...

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Bibliografische gegevens
Gepubliceerd in:J Alzheimers Dis
Hoofdauteurs: Sutovsky, Stanislav, Petrovic, Robert, Fischerova, Maria, Haverlikova, Viera, Ukropcova, Barbara, Ukropec, Jozef, Turcani, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: IOS Press 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683064/
https://ncbi.nlm.nih.gov/pubmed/32804129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200321
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