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Systematic Detection of Epistatic Interactions Based on Allele Pair Frequencies

Epistatic genetic interactions are key for understanding the genetic contribution to complex traits. Epistasis is always defined with respect to some trait such as growth rate or fitness. Whereas most existing epistasis screens explicitly test for a trait, it is also possible to implicitly test for...

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Bibliographic Details
Main Authors: Ackermann, Marit, Beyer, Andreas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276547/
https://ncbi.nlm.nih.gov/pubmed/22346757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002463
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