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Generation of liver bipotential organoids with a small-molecule cocktail
Understanding the mechanism of how cholangiocytes (liver ductal cells) are activated upon liver injury and specified to hepatocytes would permit liver regenerative medicine. Here we achieved long-term in vitro expansion of mouse liver organoids by modulating signaling pathways with a combination of...
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| Publicado no: | J Mol Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7683013/ https://ncbi.nlm.nih.gov/pubmed/32232340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjaa010 |
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