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Talin-activated vinculin interacts with branched actin networks to initiate bundles

Vinculin plays a fundamental role in integrin-mediated cell adhesion. Activated by talin, it interacts with diverse adhesome components, enabling mechanical coupling between the actin cytoskeleton and the extracellular matrix. Here we studied the interactions of activated full-length vinculin with a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Boujemaa-Paterski, Rajaa, Martins, Bruno, Eibauer, Matthias, Beales, Charlie T, Geiger, Benjamin, Medalia, Ohad
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682986/
https://ncbi.nlm.nih.gov/pubmed/33185186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53990
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