Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer

Tumor metastasis is the major cause of poor prognosis and mortality in colorectal cancer (CRC). However, early diagnosis of highly metastatic CRC is currently difficult. In the present study, we screened for a novel biomarker, GDNF family receptor alpha 1 (GFRA1) based on the expression and methylat...

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出版年:PLoS Genet
主要な著者: Dong, Zhexu, Dai, Lei, Zhang, Yong, Fang, Chao, Shi, Gang, Chen, Ye, Li, Junshu, Wang, Qin, Fu, Jiamei, Yu, Yan, Wang, Wenshuang, Cheng, Lin, Liu, Yi, Lin, Yi, Wang, Yuan, Wang, Qingnan, Wang, Huiling, Zhang, Hantao, Zhang, Yujing, Su, Xiaolan, Zhang, Shuang, Wang, Feng, Qiu, Meng, Zhou, Zongguang, Deng, Hongxin
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2020
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682896/
https://ncbi.nlm.nih.gov/pubmed/33175846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009159
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