Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer

Tumor metastasis is the major cause of poor prognosis and mortality in colorectal cancer (CRC). However, early diagnosis of highly metastatic CRC is currently difficult. In the present study, we screened for a novel biomarker, GDNF family receptor alpha 1 (GFRA1) based on the expression and methylat...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:PLoS Genet
Główni autorzy: Dong, Zhexu, Dai, Lei, Zhang, Yong, Fang, Chao, Shi, Gang, Chen, Ye, Li, Junshu, Wang, Qin, Fu, Jiamei, Yu, Yan, Wang, Wenshuang, Cheng, Lin, Liu, Yi, Lin, Yi, Wang, Yuan, Wang, Qingnan, Wang, Huiling, Zhang, Hantao, Zhang, Yujing, Su, Xiaolan, Zhang, Shuang, Wang, Feng, Qiu, Meng, Zhou, Zongguang, Deng, Hongxin
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2020
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682896/
https://ncbi.nlm.nih.gov/pubmed/33175846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009159
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