Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer

Tumor metastasis is the major cause of poor prognosis and mortality in colorectal cancer (CRC). However, early diagnosis of highly metastatic CRC is currently difficult. In the present study, we screened for a novel biomarker, GDNF family receptor alpha 1 (GFRA1) based on the expression and methylat...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Dong, Zhexu, Dai, Lei, Zhang, Yong, Fang, Chao, Shi, Gang, Chen, Ye, Li, Junshu, Wang, Qin, Fu, Jiamei, Yu, Yan, Wang, Wenshuang, Cheng, Lin, Liu, Yi, Lin, Yi, Wang, Yuan, Wang, Qingnan, Wang, Huiling, Zhang, Hantao, Zhang, Yujing, Su, Xiaolan, Zhang, Shuang, Wang, Feng, Qiu, Meng, Zhou, Zongguang, Deng, Hongxin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682896/
https://ncbi.nlm.nih.gov/pubmed/33175846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009159
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