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Impact of Age and Sex on Alpha-Synuclein siRNA-mediated Post-Stroke Recovery

BACKGROUND AND PURPOSE: Increased expression of α-Synuclein (α-Syn) is known to mediate secondary brain damage after stroke. We presently studied if α-Syn siRNA can protect ischemic brain irrespective of sex and age. METHODS: Adult and aged male and female mice were subjected to transient middle cer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Stroke
Hauptverfasser: Chelluboina, Bharath, Kim, Taehee, Mehta, Suresh L., Kim, JooYong, Bathula, Saivenkateshkomal, Vemuganti, Raghu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682747/
https://ncbi.nlm.nih.gov/pubmed/32819195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.120.028978
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