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Transient focal ischemia significantly alters the m(6)A epitranscriptomic tagging of RNAs in the brain

BACKGROUND AND PURPOSE: Adenosine in many types of RNAs can be converted to N(6)-methyladenosine (m(6)A) which is a highly dynamic epitranscriptomic modification that regulates RNA metabolism and function. Of all organs, the brain shows the highest abundance of m(6)A methylation of RNAs. As recent s...

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Publicado en:Stroke
Autores principales: Chokkalla, Anil K, Mehta, Suresh L., Kim, TaeHee, Chelluboina, Bharath, Kim, Joo Yong, Vemuganti, Raghu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759411/
https://ncbi.nlm.nih.gov/pubmed/31436138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.119.026433
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