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Human keratinocytes use sphingosine 1-phosphate and its receptors to communicate S. aureus invasion and activate host defense.

Sphingosine 1-phosphate (S1P) is a bioactive lipid mediator generated when a cell membrane or its components are damaged by various factors. S1P regulates diverse cell activities via S1P receptors (S1PRs). Keratinocytes express S1PR1-5. Though it is known that S1PRs control keratinocyte differentiat...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Igawa, Satomi, Choi, Jae Eun, Wang, Zhenping, Chang, Yu-Ling, Wu, Chia Chi, Werbel, Tyler, Ishida-Yamamoto, Akemi, Nardo, Anna Di
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682680/
https://ncbi.nlm.nih.gov/pubmed/30807768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2019.02.010
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