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The MscS-like channel YnaI has a gating mechanism based on flexible pore helices

The mechanosensitive channel of small conductance (MscS) is the prototype of an evolutionarily diversified large family that fine-tunes osmoregulation but is likely to fulfill additional functions. Escherichia coli has six osmoprotective paralogs with different numbers of transmembrane helices. Thes...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Flegler, Vanessa Judith, Rasmussen, Akiko, Rao, Shanlin, Wu, Na, Zenobi, Renato, Sansom, Mark S. P., Hedrich, Rainer, Rasmussen, Tim, Böttcher, Bettina
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682570/
https://ncbi.nlm.nih.gov/pubmed/33148804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005641117
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