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MADloy: robust detection of mosaic loss of chromosome Y from genotype-array-intensity data

BACKGROUND: Accurate protocols and methods to robustly detect the mosaic loss of chromosome Y (mLOY) are needed given its reported role in cancer, several age-related disorders and overall male mortality. Intensity SNP-array data have been used to infer mLOY status and to determine its prominent rol...

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Publicat a:BMC Bioinformatics
Autors principals: González, Juan R., López-Sánchez, Marcos, Cáceres, Alejandro, Puig, Pere, Esko, Tonu, Pérez-Jurado, Luis A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682048/
https://ncbi.nlm.nih.gov/pubmed/33225898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03768-z
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