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Extreme Downregulation of Chromosome Y and Cancer Risk in Men

BACKGROUND: Understanding the biological differences between sexes in cancer is essential for personalized treatment and prevention. We hypothesized that the extreme downregulation of chromosome Y gene expression (EDY) is a signature of cancer risk in men and the functional mediator of the reported...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Cáceres, Alejandro, Jene, Aina, Esko, Tonu, Pérez-Jurado, Luis A, González, Juan R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492764/
https://ncbi.nlm.nih.gov/pubmed/31945786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz232
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