Genotype imputation and variability in polygenic risk score estimation

BACKGROUND: Polygenic risk scores (PRSs) are a summarization of an individual’s genetic risk for a disease or trait. These scores are being generated in research and commercial settings to study how they may be used to guide healthcare decisions. PRSs should be updated as genetic knowledgebases impr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Med
Prif Awduron: Chen, Shang-Fu, Dias, Raquel, Evans, Doug, Salfati, Elias L., Liu, Shuchen, Wineinger, Nathan E., Torkamani, Ali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682022/
https://ncbi.nlm.nih.gov/pubmed/33225976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00801-x
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg