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Genotype imputation and variability in polygenic risk score estimation
BACKGROUND: Polygenic risk scores (PRSs) are a summarization of an individual’s genetic risk for a disease or trait. These scores are being generated in research and commercial settings to study how they may be used to guide healthcare decisions. PRSs should be updated as genetic knowledgebases impr...
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| Publicado no: | Genome Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7682022/ https://ncbi.nlm.nih.gov/pubmed/33225976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00801-x |
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