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Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis

Impaired clearance in the Alzheimer's Disease (AD) brain is key in the formation of Aβ parenchymal plaques and cerebrovascular deposits known as cerebral amyloid angiopathy (CAA), present in >80% of AD patients and ~50% of non‐AD elderly subjects. Aβ deposits are highly heterogeneous, contai...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Parodi‐Rullán, Rebecca, Ghiso, Jorge, Cabrera, Erwin, Rostagno, Agueda, Fossati, Silvia
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681048/
https://ncbi.nlm.nih.gov/pubmed/33155752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13258
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