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Interplay of Carbonic Anhydrase IX With Amino Acid and Acid/Base Transporters in the Hypoxic Tumor Microenvironment

Solid tumors are challenged with a hypoxic and nutrient-deprived microenvironment. Hence, hypoxic tumor cells coordinatively increase the expression of nutrient transporters and pH regulators to adapt and meet their bioenergetic and biosynthetic demands. Carbonic Anhydrase IX (CAIX) is a membrane-bo...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Venkateswaran, Geetha, Dedhar, Shoukat
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680889/
https://ncbi.nlm.nih.gov/pubmed/33240897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.602668
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