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Carving out its niche: A role for carbonic anhydrase IX in pre-metastatic niche development
Primary tumor-associated hypoxia stimulates the production of secreted factors that mobilize bone marrow-derived cells, including immunomodulatory myeloid-derived suppressor cells (MDSCs) to pre-metastatic niches. We recently found that the hypoxia-induced enzyme carbonic anhydrase IX (CAIX) promote...
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| Veröffentlicht in: | Oncoimmunology |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4635843/ https://ncbi.nlm.nih.gov/pubmed/26587316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1048955 |
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