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Hypoxia-driven immunosuppression contributes to the pre-metastatic niche
Primary tumor cells create favorable microenvironments in secondary organs, termed pre-metastatic niches, that promote the formation of metastases. Using immune competent syngenic breast cancer mouse models, we have recently demonstrated that factors secreted by hypoxic tumor cells condition pre-met...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583916/ https://ncbi.nlm.nih.gov/pubmed/23482904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22355 |
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