Loss of protein kinase D activity demonstrates redundancy in cardiac glucose metabolism and preserves cardiac function in obesity

OBJECTIVE: Protein kinase D (PKD) signaling has been implicated in stress-induced cardiac remodeling and function as well as metabolic processes including contraction-mediated cardiac glucose uptake. PKD has recently emerged as a nutrient-sensing kinase that is activated in high-lipid environments,...

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Udgivet i:Mol Metab
Main Authors: De Jong, Kirstie A., Hall, Liam G., Renton, Mark C., Connor, Timothy, Martin, Sheree D., Kowalski, Greg M., Shaw, Christopher S., Bruce, Clinton R., Howlett, Kirsten F., McGee, Sean L.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680779/
https://ncbi.nlm.nih.gov/pubmed/33099046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101105
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