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A systematic flux analysis approach to identify metabolic vulnerabilities in human breast cancer cell lines

BACKGROUND: Increased flux through both glycolytic and oxidative metabolic pathways is a hallmark of breast cancer cells and is critical for their growth and survival. As such, targeting this metabolic reprograming has received much attention as a potential treatment approach. However, the heterogen...

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Detalhes bibliográficos
Publicado no:Cancer Metab
Main Authors: Martin, Sheree D., McGee, Sean L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935091/
https://ncbi.nlm.nih.gov/pubmed/31890204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-019-0207-x
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