Trophoblast Stem-Cell-Derived Exosomes Improve Doxorubicin-Induced Dilated Cardiomyopathy by Modulating the let-7i/YAP Pathway

Trophoblast stem cells (TSCs) have been confirmed to play a cardioprotective role in heart failure. However, whether TSC-derived exosomes (TSC-exos) can protect against cardiac injury remains unclear. In the present study, TSC-exos were isolated from the supernatant of TSCs using the ultracentrifuga...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Ni, Jie, Liu, Yihai, Wang, Kun, Wu, Mingyue, Kang, Lina, Sha, Dujuan, Xu, Biao, Gu, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680701/
https://ncbi.nlm.nih.gov/pubmed/33294288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.014
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