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Mast cell recruitment is modulated by hairless skin microbiome

Hairless mice have countless mast cells (MCs) in the skin and a more gram positive microbiome (GPM). MC number normalizes when TLR2, a GPM sensor, is deleted, proving a connection between hair-loss, GPM and MCs.

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Wu, Chia-Chi, Kim, Jinwoo, Wang, Zhenping, Chang, Yu-Ling, Zengler, Karsten, Di Nardo, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680643/
https://ncbi.nlm.nih.gov/pubmed/30928651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.02.033
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