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Skin microbiome promotes mast cell maturation by triggering stem cell factor (SCF) production in keratinocytes

BACKGROUND: Mast cell (MC) progenitors leave the bone marrow, enter the circulation, and settle in the skin and other tissues. Their maturation in tissues is influenced by the surrounding microenvironment. OBJECTIVE: We tested the hypothesis that environmental factors play a role in MC maturation in...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Wang, Zhenping, Mascarenhas, Nicholas, Eckmann, Lars, Miyamoto, Yukiko, Sun, Xiaojun, Kawakami, Toshiaki, Di Nardo, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385284/
https://ncbi.nlm.nih.gov/pubmed/27746235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.09.019
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