COX-2 Inhibition Antagonizes Intra-Accumbens 2-Arachidonoylglycerol–Mediated Reduction in Ethanol Self-Administration in Rats

BACKGROUND: Ethanol (EtOH) self-administration is particularly sensitive to the modulation of CB(1) signaling in the nucleus accumbens (NAc) shell, and EtOH consumption increases extracellular levels of the endogenous cannabinoid CB(1) receptor agonist 2-arachidonoyl glycerol (2-AG) in this brain re...

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發表在:Alcohol Clin Exp Res
Main Authors: Pavon, Francisco J., Polis, Ilham, Stouffer, David G., Roberto, Marisa, Martin-Fardon, Rémi, de Fonseca, Fernando Rodriguez, Parsons, Loren H., Serrano, Antonia
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680444/
https://ncbi.nlm.nih.gov/pubmed/32944989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14456
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