Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine-induced dopamine release in the mouse nucleus accumbens

Nicotine exerts its rewarding effects by promoting an increase in dopamine (DA) release in the nucleus accumbens (NAc) and this process is influenced by the endocannabinoid system. Fatty acid amide hydrolase (FAAH) is the main enzyme responsible for the degradation of the endocannabinoid anandamide...

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Publicat a:Addict Biol
Autors principals: Pavon, Francisco J., Serrano, Antonia, Sidpura, Nimish, Polis, Ilham, Stouffer, David, de Fonseca, Fernando Rodriguez, Cravatt, Benjamin F., Martin-Fardon, Rémi, Parsons, Loren H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747548/
https://ncbi.nlm.nih.gov/pubmed/28660730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12531
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