Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine-induced dopamine release in the mouse nucleus accumbens

Nicotine exerts its rewarding effects by promoting an increase in dopamine (DA) release in the nucleus accumbens (NAc) and this process is influenced by the endocannabinoid system. Fatty acid amide hydrolase (FAAH) is the main enzyme responsible for the degradation of the endocannabinoid anandamide...

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發表在:Addict Biol
Main Authors: Pavon, Francisco J., Serrano, Antonia, Sidpura, Nimish, Polis, Ilham, Stouffer, David, de Fonseca, Fernando Rodriguez, Cravatt, Benjamin F., Martin-Fardon, Rémi, Parsons, Loren H.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747548/
https://ncbi.nlm.nih.gov/pubmed/28660730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12531
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