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Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery

Decoding molecular flexibility in order to understand and predict biological processes—applying the principles of dynamic-structure-activity relationships (DSAR)—becomes a necessity when attempting to design selective and specific inhibitors of a protein that has overlapping interaction surfaces wit...

詳細記述

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書誌詳細
出版年:Cancer Metastasis Rev
主要な著者: Pálfy, Gyula, Menyhárd, Dóra K., Perczel, András
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680338/
https://ncbi.nlm.nih.gov/pubmed/32815102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09917-3
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