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Current therapy of KRAS-mutant lung cancer
KRAS mutations are the most frequent gain-of-function alterations in patients with lung adenocarcinoma (LADC) in the Western world. Although they have been identified decades ago, prior efforts to target KRAS signaling with single-agent therapeutic approaches such as farnesyl transferase inhibitors,...
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| Pubblicato in: | Cancer Metastasis Rev |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer US
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7680319/ https://ncbi.nlm.nih.gov/pubmed/32548736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09903-9 |
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