KRAS-mutation incidence and prognostic value are metastatic site-specific in lung adenocarcinoma: poor prognosis in patients with KRAS mutation and bone metastasis

Current guidelines lack comprehensive information on the metastatic site-specific role of KRAS mutation in lung adenocarcinoma (LADC). We investigated the effect of KRAS mutation on overall survival (OS) in this setting. In our retrospective study, 500 consecutive Caucasian metastatic LADC patients...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Lohinai, Zoltan, Klikovits, Thomas, Moldvay, Judit, Ostoros, Gyula, Raso, Erzsebet, Timar, Jozsef, Fabian, Katalin, Kovalszky, Ilona, Kenessey, István, Aigner, Clemens, Renyi-Vamos, Ferenc, Klepetko, Walter, Dome, Balazs, Hegedus, Balazs
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209707/
https://ncbi.nlm.nih.gov/pubmed/28051122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39721
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