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STAT4 targets KISS1 to promote the apoptosis of ovarian granulosa cells

BACKGROUND: In mammals, it is known that the estradiol-17β (E2) is mainly synthetized in ovarian granulosa cells (GCs), and the excessive apoptosis of GCs induces the follicular atresia. Many studies have implicated the essential role of KISS1, with the pro-synthetic effect of E2 and the anti-apopto...

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Dades bibliogràfiques
Publicat a:J Ovarian Res
Autors principals: Jiang, Yao, Xin, Xiaoping, Pan, Xiangchun, Zhang, Ailing, Zhang, Zhe, Li, Jiaqi, Yuan, Xiaolong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679982/
https://ncbi.nlm.nih.gov/pubmed/33218349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-020-00741-5
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